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RF300 System
RF300 is optimized for round the clock operation and allows separate screening methods for each plate.
Cartridge Cassette for RF300
Capable of loading 6 columns at once for 24-hour operation.
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RF300 for in vitro ADME and High-throughput Screening
Faster ADME data - No compromises in assay integrity
The RF300 Mass Spectrometry System (RF-MS) is optimized for in vitro ADME applications. It was developed to address the sample processing bottleneck that face researchers today. You can take advantage of this innovative high-throughput technology using our in-house research services too.
RF300 System Features
- Label-free detection—detection of native compounds without the need for fluorescence, luminescence or radioactivity.
- Unattended operation—automated cartridge changing hardware and integrated optical sensors automatically detect fluid flow and the software flags any aberrant samples.
- Advanced plate mapping functionality—enables flexibility to use separate screening methods for each individual plate well.
- Integrated sample preparation—no up-front sample preparation required.
- Multiple cartridge chemistries available.
In vitro ADME Applications
- CYP Inhibition
- Metabolic Stability
- P-glycoprotein Inhibition (Digoxin)
- Plasma Protein Binding
- Permeability (Caco-2 and PAMPA)
- CYP Induction
The RF300 uses a cartridge cassette that enables loading of six columns at once for 24-hour unattended operation or method development using multiple chemistries per run.
BIOCIUS. Faster Answers.
RapidFire® technology is described in patent numbers 6,932,939, 6,812,030 7,100,460, 7,588,725,